In this holiday season, we've already seen how fatigue can end in possible tragedy. Uploaded last week, this video shows how it doesn't matter about the car you drive or its ability, but how careful we need to be as drivers.
Thankfully nothing ends badly for these drivers, but as you can see it could very well end with a fatality. Our being on the road is a privilege and not a right, meaning we need to keep our driving in check if we want to remain alive, or not have the death of another human on our conscience.
The salient point is how well we know the road. If you're not sure, slow down. Some corners can tighten up very quickly as some of these drivers found out the hard way.